期刊
NANOSCALE ADVANCES
卷 1, 期 12, 页码 4679-4682出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9na00498j
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资金
- National Institute for Dental and Craniofacial Research of the National Institutes of Health [R01DE026117]
- NSF through the MRSEC program
Hydrophobicity and charge are key properties of antimicrobial peptides (AMPs). We compared the self-assembly performance and its correlation with antimicrobial activity of a designer AMP and analogues with substitution of hydrophobic or cationic residues by alanine. Peptides that formed supramolecular self-assemblies under the studied conditions were those that have higher antimicrobial potency.
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