期刊
DIABETES & METABOLISM
卷 41, 期 2, 页码 145-151出版社
MASSON EDITEUR
DOI: 10.1016/j.diabet.2014.09.004
关键词
Type 1 diabetes; Type 2 diabetes; Obesity; Cardiovascular risk; Diabetes complications
资金
- Giltech Ltd, Ayrshire, Scotland
Aims. - In this cross-sectional study, the aims were to investigate the association of the socioeconomic status and gender on the prevalence of type 1 and 2 diabetes, glycaemic control, cardiovascular risk factors plus the complications of diabetes in a population-based analysis in the county of Ayrshire and Arran, Scotland. Methods. - Quality Outcome Framework data was obtained from General Practices in Ayrshire and Arran, Scotland (n=15,351 patients). Results. - In type 1 diabetes, there was an increasing linear trend in HbA(1c) across deprivation levels (P <0.01). In type 1 diabetes, obesity in women (P <0.01) and increased non-fasting triglyceride levels in both men and women were associated with deprivation (P <0.05). In type 2 diabetes, there was a significant prevalence trend with deprivation for women (P <0.01) but not with glycaemic control (P = 0.12). Smoking, ischaemic heart disease and neuropathy (P <0.01) were all associated with increasing deprivation with gender differences. In type 2 diabetes, reduced HDL cholesterol (P <0.01 both genders), and percentage of people on lipid lowering therapy (men P <0.05; women P <0.01) were associated with deprivation. Smoking, ischaemic heart disease, peripheral vascular disease and neuropathy plus foot ulcers (P < 0.05) were all associated with increasing deprivation with gender differences. Conclusions. - Socioeconomic status and gender are associated with changes in glycaemic control and cardiovascular risk factors plus complication development in both type 1 and 2 diabetes. The mechanisms are unclear but follow-up of these patients should allow greater understanding. (c) 2014 Elsevier Masson SAS. All rights reserved.
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