期刊
CURRENT GREEN CHEMISTRY
卷 6, 期 3, 页码 226-241出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/2213346106666191024123452
关键词
Aziridines; organic synthesis; green chemistry; olefins; chloramine-T; imine
资金
- Russian Science Foundation Russia [18-73-00301]
- DST-RSF Major Research Project [INT/RUS/RSF/P-08]
- Russian Science Foundation [18-73-00301] Funding Source: Russian Science Foundation
Aziridines are highly versatile intermediates in organic synthesis due to their easy access and their susceptibility to ring-opening by facile C-N bond cleavage. They are synthetically very important as they are valuable precursors of amino sugars, beta-lactam antibiotics and alkaloids or present in various natural products that exhibit potent biological activities. The synthesis of this moiety from the easily available chemicals is desirable due to its tremendous use in the various branches of chemistry. Here, a short review has been reported on the synthesis of this scaffold employing different strategies under different greener conditions. Various methods have been developed in the presence of green catalysts and solvents.
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