期刊
DIABETES
卷 64, 期 11, 页码 3631-3644出版社
AMER DIABETES ASSOC
DOI: 10.2337/db15-0831
关键词
-
资金
- National Institutes of Health [R01DK078752, UC4DK104204]
Noncoding RNA and especially microRNAs (miRs) have emerged as important regulators of key processes in cell biology, including development, differentiation, and survival. Currently, over 2,500 mature miRs have been reported in humans, and considering that each miR has multiple targets, the number of genes and pathways potentially affected is huge. Not surprisingly, many miRs have also been implicated in diabetes, and more recently, some have been discovered to play important roles in the pancreatic islet, including p-cell function, proliferation, and survival. The goal of this Perspective is to offer an overview of this rapidly evolving field and the miRs involved, reveal novel networks of beta-cell miR signaling, and provide an outlook of the opportunities and challenges ahead.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据