期刊
JOURNAL OF INVESTIGATIVE DERMATOLOGY
卷 137, 期 3, 页码 561-568出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jid.2016.10.033
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资金
- Intramural NIH HHS [ZIA BC010938-08, ZIA BC010938-09, ZIA BC011558-03] Funding Source: Medline
Growing interest in microbial contributions to human health and disease has increasingly led investigators to examine the microbiome in both healthy skin and cutaneous disorders, including acne, psoriasis, and atopic dermatitis. The need for common language, effective study design, and validated methods is critical for high-quality standardized research. Features, unique to skin, pose particular challenges when conducting microbiome research. This review discusses microbiome research standards and highlights important factors to consider, including clinical study design, skin sampling, sample processing, DNA sequencing, control inclusion, and data analysis.
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