相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Inhibition of Calcium-Dependent Protein Kinase 1 (CDPK1) In Vitro by Pyrazolopyrimidine Derivatives Does Not Correlate with Sensitivity of Cryptosporidium parvum Growth in Cell Culture
Theresa B. Kuhlenschmidt et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2016)
Preassembled Single-Stranded RNA-Argonaute Complexes: A Novel Method to Silence Genes in Cryptosporidium
Alejandro Castellanos-Gonzalez et al.
JOURNAL OF INFECTIOUS DISEASES (2016)
A Novel Calcium-Dependent Kinase Inhibitor, Bumped Kinase Inhibitor 1517, Cures Cryptosporidiosis in Immunosuppressed Mice
Alejandro Castellanos-Gonzalez et al.
JOURNAL OF INFECTIOUS DISEASES (2016)
Novel Bumped Kinase Inhibitors Are Safe and Effective Therapeutics in the Calf Clinical Model for Cryptosporidiosis
Deborah A. Schaefer et al.
JOURNAL OF INFECTIOUS DISEASES (2016)
Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis
Rama Subba Rao Vidadala et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium
William Checkley et al.
LANCET INFECTIOUS DISEASES (2015)
Genetic modification of the diarrhoeal pathogen Cryptosporidium parvum
Sumiti Vinayak et al.
NATURE (2015)
Pathogen-specific burdens of community diarrhoea in developing countries: a multisite birth cohort study (MAL-ED)
James A. Platts-Mills et al.
LANCET GLOBAL HEALTH (2015)
High-risk enteric pathogens associated with HIV infection and HIV exposure in Kenyan children with acute diarrhoea
Patricia B. Pavlinac et al.
AIDS (2014)
Identification of Cryptosporidium parvum Active Chemical Series by Repurposing the Open Access Malaria Box
Kovi Bessoff et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2014)
A Specific Inhibitor of PfCDPK4 Blocks Malaria Transmission: Chemical-genetic Validation
Kayode K. Ojo et al.
JOURNAL OF INFECTIOUS DISEASES (2014)
Substituted 2-Phenylimidazopyridines: A New Class of Drug Leads for Human African Trypanosomiasis
Hari Babu Tatipaka et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
The gatekeeper residue and beyond: homologous calcium-dependent protein kinases as drug development targets for veterinarian Apicomplexa parasites
Katelyn R. Keyloun et al.
PARASITOLOGY (2014)
Ontogeny of Human Hepatic and Intestinal Transporter Gene Expression during Childhood: Age Matters
Miriam G. Mooij et al.
DRUG METABOLISM AND DISPOSITION (2014)
Drug disposition and clinical practice in neonates: Cross talk between developmental physiology and pharmacology
Anne Smits et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2013)
A Novel Calcium-Dependent Protein Kinase Inhibitor as a Lead Compound for Treating Cryptosporidiosis
Alejandro Castellanos-Gonzalez et al.
JOURNAL OF INFECTIOUS DISEASES (2013)
Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study
Karen L. Kotloff et al.
LANCET (2013)
Distinct signalling pathways control Toxoplasma egress and host-cell invasion
Sebastian Lourido et al.
EMBO JOURNAL (2012)
Transmission of malaria to mosquitoes blocked by bumped kinase inhibitors
Kayode K. Ojo et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Development of Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitors with Potent Anti-Toxoplasma Activity
Steven M. Johnson et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Reducing safety-related drug attrition: the use of in vitro pharmacological profiling
Joanne Bowes et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
Comparison of Human Ether-a-go-go Related Gene Screening Assays Based on IonWorks Quattro and Thallium Flux
Terry R. Bridal et al.
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2010)
Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma
Sebastian Lourido et al.
NATURE (2010)
Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors
Kayode K. Ojo et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Discovery of Potent and Selective Inhibitors of CDPK1 from C. parvum and T. gondii
Ryan C. Murphy et al.
ACS MEDICINAL CHEMISTRY LETTERS (2010)
Calcium-Dependent Signaling and Kinases in Apicomplexan Parasites
Oliver Billker et al.
CELL HOST & MICROBE (2009)
Calcium and a calcium-dependent protein kinase regulate gamete formation and mosquito transmission in a malaria parasite
O Billker et al.
CELL (2004)
Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development
WS Redfern et al.
CARDIOVASCULAR RESEARCH (2003)
Effect of nitazoxanide on morbidity and mortality in Zambian children with cryptosporidiosis: a randomised controlled trial
B Amadi et al.
LANCET (2002)
Cryptosporidiosis and the challenges of chemotherapy
JR Mead
DRUG RESISTANCE UPDATES (2002)
Epidemiology and clinical features of Cryptosporidium infection in immunocompromised patients
PR Hunter et al.
CLINICAL MICROBIOLOGY REVIEWS (2002)
Treatment of diarrhea caused by Cryptosporidium parvum:: A prospective randomized, double-blind, placebo-controlled study of nitazoxanide
JFA Rossignol et al.
JOURNAL OF INFECTIOUS DISEASES (2001)
Toxoplasma gondii attachment to host cells is regulated by a calmodulin-like domain protein kinase
H Kieschnick et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
分享论文
