期刊
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
卷 46, 期 -, 页码 182-191出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jiec.2016.10.029
关键词
Graphene oxide; Chitosan; Hyaluronic acid; Simvastatin; Bone tissue engineering
资金
- Basic Science Research Program through National Research Foundation of Korea (NRF) by Ministry of Education, Science and Technology [NRF-2016H1D3A1938077, 2016R1D1A1B03934124]
- National Research Foundation of Korea [2016R1D1A1B03934124, 2016H1D3A1938077] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
The present study explores the first ever fabrication of graphene oxide (GO)Chitosan (CS)Hyaluronic acid (HA) based bioactive composite scaffold containing an osteogenesis-inducing drug simvastatin (SV) for bone tissue engineering application. Porosity, density, swelling, degradation and biomineralization studies favored the SV loaded GOCSHA scaffold in comparison to the conventional CS and HA based scaffolds. The in vitro results showed that the SV also offers a significant influence on osteogenesis and biomineralization and it possess excellent biocompatibility to be used as a bone tissue engineering scaffold, which is able to persuade osteogenesis and mineralization. (C) 2016 Published by Elsevier B.V. on behalf of The Korean Society of Industrial and Engineering Chemistry.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据