期刊
DEVELOPMENTAL CELL
卷 33, 期 1, 页码 107-118出版社
CELL PRESS
DOI: 10.1016/j.devcel.2015.01.025
关键词
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资金
- NIH [1R01GM086632, S10RR029668, S10RR027303]
- German Academic Exchange Service
- NSF graduate research fellowship
- Swiss National Science Foundation
- EMBO Long-term Fellowship
- Belgian American Educational Foundation
- Belgian National Fund for Scientific Research
- NIH Shared Instrument Grant [S10RR025518-01]
- [NIH5T32GM007276]
Developmental transitions can be described in terms of morphology and the roles of individual genes, but also in terms of global transcriptional and epigenetic changes. Temporal dissections of transcriptome changes, however, are rare for intact, developing tissues. We used RNA sequencing and microarray platforms to quantify gene expression from labeled cells isolated by fluorescence-activated cell sorting to generate cell-type-specific transcriptomes during development of an adult stem-cell lineage in the Arabidopsis leaf. We show that regulatory modules in this early lineage link cell types that had previously been considered to be under separate control and provide evidence for recruitment of individual members of gene families for different developmental decisions. Because stomata are physiologically important and because stomatal lineage cells exhibit exemplary division, cell fate, and cell signaling behaviors, this dataset serves as a valuable resource for further investigations of fundamental developmental processes.
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