4.5 Article

Yeasticidal activity of chemical disinfectants and antiseptics against Candida auris

期刊

JOURNAL OF HOSPITAL INFECTION
卷 97, 期 4, 页码 371-375

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W B SAUNDERS CO LTD
DOI: 10.1016/j.jhin.2017.08.019

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Candida auris; Quantitative suspension test; Chlorine; Chlorhexidine gluconate; Povidone-iodine

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  1. Public Health England

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Candida auris appears to be transmitted readily between patients, yet information regarding the efficacy of environmental disinfection and skin decolonization is lacking. A quantitative suspension test (EN 13624:2013) was used to evaluate the yeasticidal activity of different chemical disinfectants and antiseptics against C. auris and Candida albicans. When tested in suspension, both a chlorine-based disinfectant and iodine-based skin antiseptic were effective against C. auris, suggesting that their use could reduce environmental contamination and skin colonization, respectively, if applied appropriately. Chlorhexidine-based products may also be effective. However, in this study, activity depended on formulation, specifically the presence of isopropyl alcohol. Crown Copyright (C) 2017 Published by Elsevier Ltd on behalf of The Healthcare Infection Society. All rights reserved.

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