期刊
CHEMICAL COMMUNICATIONS
卷 55, 期 88, 页码 13215-13218出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc06782e
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资金
- National Natural Science Foundation of China [21777037]
- State Key Laboratory of Pollution Control and Resource Reuse Foundation [PCCRF16004]
- CAS Key Laboratory of Urban Pollutant Conversion [KF201603]
We herein communicate the DNase I like activity of nanoceria (CeO2 nanoparticles). Both CeO2 and DNase I cleave polyadenine (poly-A) DNA down to similar to 5-mer fragments as the major products, although further cleavage to even shorter fragments was observed with CeO2. Mass spectrometry indicates a hydrolytic cleavage mechanism instead of oxidative cleavage.
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