期刊
CHINESE JOURNAL OF ORGANIC CHEMISTRY
卷 39, 期 12, 页码 3338-3352出版社
SCIENCE PRESS
DOI: 10.6023/cjoc201904068
关键词
heteroatom; imidazole-fused heterocycles; transition metal-free; reaction mechanism
资金
- Young Scholars Research Fund of Yantai University [HY19B06]
Recently, the direct incorporation of heteroatom into imidazole-fused heterocycles through transition metal-free C-H functionalization has rapidly been advanced and become an eco-friendly synthetic tool for the synthesis of functionalized natural or bioactive molecules such as (hetero)arenes, olefins, carbonyl compounds. In particular, the C-H functionalization of imidazole-fused heterocycles has been considered to be the most important since it can lead to a new class of biologically active compounds. The recent progress in the incorporation of heteroatom into imidazole-fused heterocycles through transition metal-free C-H functionalization is introduced, and their mechanisms from a new perspective are also elaborated.
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