期刊
JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
卷 24, 期 9, 页码 501-510出版社
WILEY
DOI: 10.1002/jhbp.492
关键词
Pancreaticoduodenectomy; Postoperative complication mortality; Process of care; Quality indicator
资金
- Japanese Society for Clinical Pathway
BackgroundThe aim of the present study was to assess recent trends in pancreaticoduodenectomy (PD) and the role of institutional standardization on the development of postoperative complications in 3,378 patients who underwent PD in Japan. MethodsData were collected from 3,378 patients who underwent PD in 2006, 2010 and 2014 at 53 institutions. A standardized institution (SI) was defined as one that implements 7 of 13 quality initiatives according to departmental policy. There were 1,223 patients in the SI group and 2,155 in the non-SI group. Clinical parameters were compared over time, and between groups. Risk factors for morbidity and mortality were assessed by logistic regression analysis with a mixed-effects model. ResultsThe number of patients who underwent PD in SIs increased from 16.5% in 2006 to 46.4% in 2014. The SI group experienced an improved process of care and a lower frequency of severe complications vs. the non-SI group (P < 0.001). Multivariate analysis revealed that the SI group was associated with a lower incidence of delayed gastric emptying (odds ratio -0.499, P = 0.008) and incisional surgical site infection (odds ratio -0.999, P < 0.001). ConclusionStandardization of care in PD may be important in reducing post-PD complications, and is a critical element for improving clinical outcomes.
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