期刊
JOURNAL OF GERONTOLOGICAL NURSING
卷 43, 期 5, 页码 39-48出版社
SLACK INC
DOI: 10.3928/00989134-20170131-01
关键词
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资金
- Aljoya Endowed Professorship
- Healthy Brain Research Network (HBRN) - Centers for Disease Control and Prevention's (CDC) Alzheimer's Disease and Healthy Aging Program
- [U48 DP 005013]
Single-component interventions for modifiable risk factors to improve cognitive function in older adults have limited impacts. Multi-component interventions may be more effective. The current review describes randomized trials of multi-component interventions, and reports the state of the evidence to protect the cognitive health and reduce the risk of cognitive decline among middle-aged and older adults. Two hundred seventy- nine studies were found through electronic databases, 30 full-text reviews were completed, and six studies were identified for final selection. Findings suggest that a multi-component approach is promising compared to single-component interventions. Most multi-component intervention studies found improvement in at least one domain of cognitive function. However, the quality of multi-component studies was largely fair or poor primarily due to small samples and short trial durations. There is a need for more rigorous studies of multi-component interventions and to refine the knowledge on the specific interventions that optimize prevention domains.
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