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S. Herrmann et al.
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Zhandi Liao et al.
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Marco Lolicato et al.
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Mirko Baruscotti et al.
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Edward G. Lakatta et al.
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Design of aging intervention studies: the NIA interventions testing program
N. L. Nadon et al.
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Xin Huang et al.
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Jie Liu et al.
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Bradycardic and proarrhythmic properties of sinus node inhibitors
J Stieber et al.
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TM Vinogradova et al.
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C Marionneau et al.
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RB Clark et al.
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S Moosmang et al.
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