期刊
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
卷 33, 期 1, 页码 99-110出版社
WILEY
DOI: 10.1111/jgh.13987
关键词
abdominal pain; antispasmodics; Asia; bloating; cross-cultural research; diet; irritable bowel syndrome; Rome criteria
资金
- Menarini Asia-Pacific, Singapore
Historically, the epidemiology of gastrointestinal diseases in Asia was different from that in Western countries. Early studies suggested a low prevalence of irritable bowel syndrome (IBS) in Asia. As the diagnosis of IBS is symptom-based and as symptom perception, expression, and interpretation are influenced by sociocultural perspectives including language, the presentation of IBS is expected to vary in different communities. Furthermore, the pathogenesis is multifactorial with psychosocial (stress, illness, behavior, and diet) and biological (infection, gut microbiota, and immune activation) variables interacting, and so, the present study can anticipate that the development of IBS will vary in different environments. In recognition of this aspect of functional gastrointestinal disorders, the recently published Rome IV documents have provided greater focus on cross-cultural factors. In this review, the present study seeks to highlight Asian perspectives by identifying historical trends and recent publications from the region and comparing these with the observations from Western societies.
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