期刊
CURRENT ENVIRONMENTAL HEALTH REPORTS
卷 6, 期 4, 页码 214-224出版社
SPRINGERNATURE
DOI: 10.1007/s40572-019-00256-2
关键词
Triclosan; Parabens; Children's health; Eczema; Asthma; Immune system
资金
- NIEHS NIH HHS [F32 ES029812] Funding Source: Medline
Purpose of ReviewWe examined recent research on associations of prenatal and early-childhood exposure to the antimicrobial compounds, triclosan, and parabens, with the risk of asthma and eczema in children. We will discuss potential biological mechanisms of this association and highlight strengths and limitations of the study design and exposure assessment of current findings.Recent FindingsResults of available toxicological and epidemiologic studies indicate a potential link of triclosan and paraben exposures with asthma and eczema in children, as well as changes in microbiome diversity and immune dysfunction, which could possibly mediate an association with the health outcomes.SummaryA small number of studies suggest that triclosan and paraben exposures could be related to the risk of asthma and eczema in children. Although current findings are far from conclusive, there is emerging evidence that changes in microbiome diversity and immune function from antimicrobial exposure may mediate these relations.
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