期刊
CHEMICAL SOCIETY REVIEWS
卷 49, 期 1, 页码 114-142出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cs00466a
关键词
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资金
- General Research Fund [17306315, 17329516, 17304017, 17304418, 17307919]
- Research Grants Council of Hong Kong [C6004-14G]
- Seed Funding Programme for Basic Research [201811159241, 201711159249]
- Seed Funding for Strategic Interdisciplinary Research Scheme from the University of Hong Kong
- Sichuan Science and Technology Program [2018JZ0026]
Aqueous two-phase systems (ATPSs) have been recognized for their applications in extraction, separation, purification, and enrichment of (bio)molecules and cells. Recently, their unique ability to create aqueous-aqueous interfaces through phase separation and the characteristics of these interfaces have created new opportunities in biomedical applications. In this review, we summarize recent progress in understanding the dynamics at aqueous-aqueous interfaces, and in developing interface-assisted design of artificial cells and cyto-mimetic materials, fabrication of cyto- and bio-compatible microparticles, cell micropatterning, 3D bioprinting, and microfluidic separation of cells and biomolecules. We also discuss the challenges and perspectives to leverage the unique characteristics of ATPSs and their interfaces in broader applications.
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