期刊
JOURNAL OF CONTROLLED RELEASE
卷 256, 期 -, 页码 9-18出版社
ELSEVIER
DOI: 10.1016/j.jconrel.2017.04.019
关键词
Nano-systems; Quality by design; Design of experiment; Process analytical technology
资金
- National Natural Science Foundation of China [81303218]
- Beijing Nova Program of China [xx2016050]
- Science Fund for Distinguished Young Scholars in BUCM [2015-JYB-XYQ-003]
Quality by design (QbD) has become an inevitable trend because of its benefits for product quality and process understanding. Trials have been conducted using QbD in nanosystems' optimization. This paper reviews the application of QbD for processing nanosystems and summarizes the application procedure. It provides prospective guidelines for future investigations that apply QbD to nanosystem manufacturing processes. Employing the QbD concept in this way is a novel area in nanosystem quality.
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