期刊
YONSEI MEDICAL JOURNAL
卷 61, 期 1, 页码 100-102出版社
YONSEI UNIV COLL MEDICINE
DOI: 10.3349/ymj.2020.61.1.100
关键词
Autoimmune hepatitis; acute hepatitis A; regulatory T cells; inflammatory conversion of Treg cells
To evaluate the pathophysiology of autoimmune hepatitis (AIH) following acute hepatitis A (AHA) in immunologic aspects, we performed multi-color flow cytometry with peripheral blood mononuclear cells of a patient who underwent liver transplantation due to AIH-induced liver failure. Unlike general AHA patients, the proportion of tumor necrosis factor-a-producing Treg cells remained high for 6 months after diagnosis of AHA until she underwent a liver transplantation. The conversion of Treg cells into mediators of inflammation may have played a role in the autoimmune pathogenesis following AHA.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据