期刊
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
卷 167, 期 2, 页码 -出版社
ELECTROCHEMICAL SOC INC
DOI: 10.1149/1945-7111/ab61e7
关键词
-
The aromatic amino acids tyrosine (TY) and tryptophan (TP) are important as precursors of catecholamines and 5-hydroxytryptamine. An innovative strategy was proposed in preparation of a novel layered sensor based on layer-by-layer modification of a glassy carbon electrode surface (GC) with graphene (RGO), ionic liquid crystal (ILC), multi-walled carbon nanotubes (CNT) and Fe-Zn nano-alloy (GC/RGO/ILC/CNT/Fe-Zn). The conductive layered electrode offered good sensitivities and low detection limit values for determination of tyrosine (TY) and tryptophan (TP) due to the synergistic impact of its components. A major problem expected during electrochemical assays of TY or TP in human biological fluids is overlap of their current responses with ascorbic acid (AA) and uric acid (UA) compounds when using the unmodified electrodes. Thus, the proposed sensor resolved this problem and exhibited excellent electrocatalytic activity towards determination of TY or TP in presence of AA and UA in human serum with low detection limit values 5.1 nM, 86 nM, 2.6 nM for TY, AA and UA and 3.8 nM, 91 nM, 2.9 nM for TP, AA and UA, respectively. Moreover, the proposed sensor displayed good sensitivity towards simultaneous determination of dopamine (DA) and serotonin (ST) with TY or TP. Recovery tests of TY and TP compounds were successful. (C) 2020 The Electrochemical Society (ECS). Published on behalf of ECS by IOP Publishing Limited.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据