期刊
CHEMICAL COMMUNICATIONS
卷 56, 期 4, 页码 615-618出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc07257h
关键词
-
资金
- EPSRC [EP/L020599/1]
- University of Reading
- FAPESP
- CNPq [2016/24409-3, 307017/2016-8]
- CAPES
- Diamond Light Source
- Brazilian Nanotechnology National Laboratory [AFM-22756, AFM-24618]
- EPSRC [EP/L020599/1] Funding Source: UKRI
Three model arginine-rich tripeptides RXR (X = W, F or non-natural residue 2-napthylalanine) were investigated as antimicrobial agents, with a specific focus to target Pseudomonas aeruginosa through membrane lysis. Activity against biofilms was related to binding of the second messenger molecule, nucleotide bis-(3 '-5 ')-cyclic dimeric guanosine monophosphate (c-di-GMP). Strong selective activity against P. aeruginosa in planktonic form was observed for RFR and RWR.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据