期刊
JOURNAL OF CLINICAL NEUROPHYSIOLOGY
卷 34, 期 4, 页码 300-306出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/WNP.0000000000000377
关键词
Island of Reil; Meta-analysis; Functional connectivity; Parcellation
资金
- National Institute of Mental Health [R01MH107549]
- NARSAD Young Investigator Award
The insular cortex, or Island of Reil, is hidden deep within the lateral sulcus of the brain. Subdivisions within the insula have been identified on the basis of cytoarchitectonics, sulcal landmarks, and connectivity. Depending on the parcellation technique used, the insula can be divided into anywhere between 2 and 13 distinct subdivisions. The insula subserves a wide variety of functions in humans ranging from sensory and affective processing to high-level cognition. Here, we provide a concise summary of known structural and functional features of the human insular cortex with a focus on lesion case studies and recent neuroimaging evidence for considerable functional heterogeneity of this brain region.
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