期刊
JOURNAL OF CLINICAL MICROBIOLOGY
卷 55, 期 5, 页码 1269-1275出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00017-17
关键词
foodborne pathogens; genome analysis; molecular subtyping; surveillance studies
类别
资金
- European Food Safety Authority [GP/EFSA/AFSCO/2015/01/CT2]
- INNUENDO project
This review describes the current state of knowledge regarding the application of whole-genome sequencing (WGS) in the epidemiology of Campylobacter jejuni, the leading cause of bacterial gastroenteritis worldwide. We describe how WGS has increased our understanding of the evolutionary and epidemiological dynamics of this pathogen and how WGS has the potential to improve surveillance and outbreak detection. We have identified hurdles to the full implementation of WGS in public health settings. Despite these challenges, we think that ample evidence is available to support the benefits of integrating WGS into the routine monitoring of C. jejuni infections and outbreak investigations.
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