期刊
CHEMICAL SOCIETY REVIEWS
卷 49, 期 4, 页码 1041-1056出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cs00129h
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资金
- Research Grants Council of the Hong Kong Special Administrative Region [11303517]
- NIH [PO1CA055791]
- TPCI Support Grant [P30CA16056]
- MINECO [CTQ2017-85393-P]
- ERA-NET/MINECO [EuroNanoMed2017-191/PCIN-2017-042]
- Turkish Academy of Sciences
Phthalocyanines exhibit superior photoproperties that make them a surely attractive class of photosensitisers for photodynamic therapy of cancer. Several derivatives are at various phases of clinical trials, and efforts have been put continuously to improve their photodynamic efficacy. To this end, various strategies have been applied to develop advanced phthalocyanines with optimised photoproperties, dual therapeutic actions, tumour-targeting properties and/or specific activation at tumour sites. The advantageous properties and potential of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer are highlighted in this tutorial review.
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