期刊
JAPANESE JOURNAL OF INFECTIOUS DISEASES
卷 73, 期 1, 页码 55-57出版社
NATL INST INFECTIOUS DISEASES
DOI: 10.7883/yoken.JJID.2019.056
关键词
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资金
- Clinical Research Division of Sendai Medical Center
- Research Program on Promoting Development of Innovative Drugs against Emerging and Reemerging Infectious Diseases at Japan Agency for Medical Research and Development (AMED)
- Japanese Initiative for Global of Research Network on Infections Diseases (J-GRID) at AMED
- Japan Society for Promotion of Scieuce (JSPS) KAKENHI
- Miuistry of Health, Labour and Welfare
We previously reported a hospital-based epidemiological study on enterovirus (EV)-D68 infection among children during the autumn of 2015, which indirectly inferred an outbreak in Sendai, Japan. In this study, stocked sera of children (aged 0-6 years; without symptoms of infectious diseases) in the Sendai community collected during 4 periods (1 year before, 6 months before, immediately after, and 1 year after the possible outbreak period) were analyzed using the neutralization antibody titer assay to determine community children's immunity levels against EV-D68 infection. The immunity levels were confirmed to have increased during the possible outbreak period and to have gradually waned over 1 year without another outbreak. These results provide background information supporting the results of our previous hospital-based surveillance study.
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