期刊
JOURNAL OF CHROMATOGRAPHY A
卷 1499, 期 -, 页码 211-216出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.chroma.2017.04.002
关键词
Ultrafast chiral separations; Enantiopurity analysis; High throughput analysis; High speed autosampler; Multiple injections in a single experimental; run
资金
- MRL Postdoctoral Research Fellows program
The combination of high speed autosampler technology and ultrafast chromatographic separations enables faster high throughput analysis. With an injection cycle time of 10.6 s, MISER (Multiple Injection in a Single Experimental Run) HPLC-MS analysis of a 96 well microplate can be completed in only 17 min. As chromatographic separations in the sub 5 s range become increasingly common, even faster autosamplers will be needed to realize further speed improvements in high throughput LC-MS analysis. Indeed with proper hardware sampling approaches, chromatographic analysis of microplates could approach speeds of spectrophotometric plate readers while maintaining the advantage of multicomponent detection and monitoring. (C) 2017 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据