期刊
CHEMICAL SCIENCE
卷 11, 期 6, 页码 1623-1628出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9sc04029c
关键词
-
资金
- [NSFC-21772218]
- [21821002]
- [XDB20000000]
A copper-catalyzed enantioselective arylalkynylation of alkenes with diaryliodonium salt and a monosubstituted alkyne is reported. The three-component coupling reactions proceed under mild reaction conditions with a broad substrate scope, leading to synthetically valuable 1,2-diaryl-3-butynes. The key to the success of this chemistry is the employment of the chiral bisoxazoline-phenylaniline (BOPA) ligand. A novel reaction pathway involving the phenyl radical generation under thermal copper catalysis is proposed according to mechanistic studies.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据