期刊
CARDIO-ONCOLOGY
卷 6, 期 1, 页码 -出版社
BMC
DOI: 10.1186/s40959-020-0059-0
关键词
Melphalan; Multiple myeloma; Autologous stem cell transplantation; Sinus arrest; Arrhythmia
High dose melphalan is commonly used as a conditioning regimen for autologous stem cell transplantation in multiple myeloma. There are reports of adverse cardiac events with melphalan manifested by supraventricular tachycardia and atrial fibrillation. Here, we report a rare case of a 58 year old female with multiple myeloma, who developed sinus arrest after autologous stem cell transplantation using high dose melphalan as a conditioning regimen. It was severe and rare, therefore, monitoring for cardiac toxicity in patients receiving high-dose melphalan is mandatory.
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