期刊
JOURNAL OF CELLULAR BIOCHEMISTRY
卷 119, 期 2, 页码 1291-1298出版社
WILEY
DOI: 10.1002/jcb.26303
关键词
CRISPR specificity; genetically modified organisms; regulatory agencies
资金
- Israel Science Foundation [268/14]
- FP7 Ideas: European Research Council [336079]
- European Research Council (ERC) [336079] Funding Source: European Research Council (ERC)
Generating plants with increased yields while maintaining low production and maintenance costs is highly important since plants are the major food source for humans and animals, as well as important producers of chemicals, pharmaceuticals, and fuels. Gene editing approaches, particularly the CRISPR-Cas system, are the preferred methods for improving crops, enabling quick, robust, and accurate gene manipulation. Nevertheless, new breeds of genetically modified crops have initiated substantial debates concerning their biosafety, commercial use, and regulation. Here, we discuss the challenges facing genetic engineering of crops by CRISPR-cas, and highlight the pros and cons of using this tool.
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