期刊
JOURNAL OF BONE AND MINERAL METABOLISM
卷 36, 期 1, 页码 1-11出版社
SPRINGER JAPAN KK
DOI: 10.1007/s00774-017-0860-5
关键词
Extracellular vesicles; Exosomes; Osteoblasts; Osteoclasts; Bone metastasis
资金
- National Natural Science Foundation of China (NSFC) [81502465]
Extracellular vesicles (EVs) are phospholipid membrane-enclosed entities containing specific proteins, RNA, miRNA, and lncRNA. EVs are released by various cells and play a vital role in cell communication by transferring their contents from the host cells to the recipient cells. The role of EVs has been characterized in a wide range of physiological and pathophysiological processes. In this context, we highlight recent advances in our understanding of the regulatory effects of EVs, with a focus on bone metabolism and the bone microenvironment. The roles of EVs in cell communication among bone-related cells, stem cells, tumor cells, and other cells under physiological or pathological conditions are also discussed. In addition, promising applications for EVs in treating bone-related diseases are proposed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据