期刊
EURASIAN CHEMICAL COMMUNICATIONS
卷 2, 期 5, 页码 563-572出版社
SAMI PUBLISHING CO-SPC
DOI: 10.33945/SAMI/ECC.2020.5.1
关键词
Epinephrine; acetylcholine; Ag-ZnO nanoplates; screen printed electrode
资金
- Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran [98000289, EC/98-28/KNRC]
Electrochemical behaviors of epinephrine and acetylcholine were investigated, using cyclic voltammetry, on the Ag-ZnO modified screen-printed electrode (Ag-ZnO/SPE). Ag-ZnO nanoplates showed excellent electrocatalytic activity toward the oxidation of epinephrine and acetylcholine compared with bare SPE in 0.1 M PBS. Under the optimized experimental conditions, a linear response obtained in the range of 0.13 to 450.00 mu M with detection limit of 0.04 mu M for epinephrine. Ag-ZnO/SPE exhibits good stability, reproducibility and repeatability, and the method has been successfully applied for detection of epinephrine and acetylcholine in their pharmaceutical and biological samples with satisfactory recovery.
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