期刊
ORGANIC CHEMISTRY FRONTIERS
卷 7, 期 5, 页码 756-762出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9qo01491h
关键词
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资金
- National Natural Science Foundation of China [21572162]
- Natural Science Foundation of Zhejiang Province [LY20B020015, LQ18B020006]
A Pd-catalyzed tandem reaction of 2-(cyanomethoxy)chalcones with thiophenes through direct C-H addition and sequential intramolecular conjugate addition/cyclization/aromatization provides a diverse range of 3-aryl-1-(thiophen-2-yl)benzofuro[2,3-c]pyridines. A representative product was assessed as a ratiometric fluorescent probe for Hg2+. This chemistry could also be applied to the synthesis of other fused ring systems.
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