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Chantal Bou-Hanna et al.
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Alokta Chakrabarti et al.
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William R. Coward et al.
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M. C. C. Sachweh et al.
CELL DEATH & DISEASE (2013)
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Suzanne Hagan et al.
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Oguz Kara et al.
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William A. Freed-Pastor et al.
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Jack T. Zilfou et al.
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Nicole Zache et al.
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Mona D. Shahbazian et al.
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B Iacopetta et al.
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U Heider et al.
EUROPEAN JOURNAL OF HAEMATOLOGY (2006)
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L Verdone et al.
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CA Corcoran et al.
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X Tong et al.
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JY Wang et al.
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SR Comeau et al.
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EF Pettersen et al.
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J Wischhusen et al.
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PA Marks et al.
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G Smith et al.
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A Eberharter et al.
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GROMACS 3.0: a package for molecular simulation and trajectory analysis
E Lindahl et al.
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KL Murphy et al.
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