相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Internalization, axonal transport and release of fibrillar forms of alpha-synuclein
Gregor Bieri et al.
NEUROBIOLOGY OF DISEASE (2018)
Proteolysis of α-synuclein fibrils in the lysosomal pathway limits induction of inclusion pathology
Amanda N. Sacino et al.
JOURNAL OF NEUROCHEMISTRY (2017)
Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins
William P. Flavin et al.
ACTA NEUROPATHOLOGICA (2017)
Effects of Serine 129 Phosphorylation on α-Synuclein Aggregation, Membrane Association, and Internalization
Filsy Samuel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Axonal transport and secretion of fibrillar forms of α-synuclein, Aβ42 peptide and HTTExon 1
Michel Brahic et al.
ACTA NEUROPATHOLOGICA (2016)
Tunneling nanotubes spread fibrillar α-synuclein by intercellular trafficking of lysosomes
Saida Abounit et al.
EMBO JOURNAL (2016)
Comparison of strategies for non-perturbing labeling of α-synuclein to study amyloidogenesis
Conor M. Haney et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2016)
Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3
Xiaobo Mao et al.
SCIENCE (2016)
Direct Observation of α-Synuclein Amyloid Aggregates in Endocytic Vesicles of Neuroblastoma Cells
Mihaela M. Apetri et al.
PLOS ONE (2016)
Tau Trimers Are the Minimal Propagation Unit Spontaneously Internalized to Seed Intracellular Aggregation
Hilda Mirbaha et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease
Fu-Lei Tang et al.
JOURNAL OF NEUROSCIENCE (2015)
α-Synuclein strains cause distinct synucleinopathies after local and systemic administration
W. Peelaerts et al.
NATURE (2015)
Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration
Katrina L. Paumier et al.
NEUROBIOLOGY OF DISEASE (2015)
Haploinsufficiency of cathepsin D leads to lysosomal dysfunction and promotes cell-to-cell transmission of α-synuclein aggregates
E-J Bae et al.
CELL DEATH & DISEASE (2015)
Progressive Aggregation of Alpha-Synuclein and Selective Degeneration of Lewy Inclusion-Bearing Neurons in a Mouse Model of Parkinsonism
Valerie R. Osterberg et al.
CELL REPORTS (2015)
Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys
Ariadna Recasens et al.
ANNALS OF NEUROLOGY (2014)
Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases
Jing L. Guo et al.
NATURE MEDICINE (2014)
Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite-like aggregates
Laura A. Volpicelli-Daley et al.
NATURE PROTOCOLS (2014)
Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death
Mathieu Bourdenx et al.
FRONTIERS IN NEUROANATOMY (2014)
α-Synuclein Immunotherapy Blocks Uptake and Templated Propagation of Misfolded α-Synuclein and Neurodegeneration
Hien T. Tran et al.
CELL REPORTS (2014)
Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons
Jessica W. Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Self-propagation of pathogenic protein aggregates in neurodegenerative diseases
Mathias Jucker et al.
NATURE (2013)
A novel α-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of α-synuclein-GFP
Christian Hansen et al.
NEUROBIOLOGY OF DISEASE (2013)
Alpha-Synuclein Induces Lysosomal Rupture and Cathepsin Dependent Reactive Oxygen Species Following Endocytosis
David Freeman et al.
PLOS ONE (2013)
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
Brandon B. Holmes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Neuron-to-neuron transmission of α-synuclein fibrils through axonal transport
Eric C. Freundt et al.
ANNALS OF NEUROLOGY (2012)
Lysosomal dysfunction in Parkinson disease ATP13A2 gets into the groove
Benjamin Dehay et al.
AUTOPHAGY (2012)
Tau Oligomers Impair Artificial Membrane Integrity and Cellular Viability
Katharina Flach et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
Kelvin C. Luk et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Action of polystyrene nanoparticles of different sizes on lysosomal function and integrity
Eleonore Froehlich et al.
PARTICLE AND FIBRE TOXICOLOGY (2012)
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
Kelvin C. Luk et al.
SCIENCE (2012)
An extracellular mechanism that can explain the neurotoxic effects of alpha-synuclein aggregates in the brain
C. Pacheco et al.
FRONTIERS IN PHYSIOLOGY (2012)
A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease
Alexander Zimprich et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2011)
VPS35 Mutations in Parkinson Disease
Carles Vilarino-Gueell et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2011)
The incidence of Parkinsonism in patients with type 1 Gaucher disease: Data from the ICGG Gaucher Registry
Barry Rosenbloom et al.
BLOOD CELLS MOLECULES AND DISEASES (2011)
α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
Christian Hansen et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
Laura A. Volpicelli-Daley et al.
NEURON (2011)
Glucocerebrosidase is present in α-synuclein inclusions in Lewy body disorders
Ozlem Goker-Alpan et al.
ACTA NEUROPATHOLOGICA (2010)
Induction of Lysosomal Dilatation, Arrested Autophagy, and Cell Death by Chloroquine in Cultured ARPE-19 Cells
Young Hee Yoon et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2010)
A novel method to determine the engulfment of apoptotic cells by macrophages using pHrodo succinimidyl ester
Michael Miksa et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2009)
Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo
Valerie Cullen et al.
MOLECULAR BRAIN (2009)
Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity
Liyan Qiao et al.
Molecular Brain (2008)
BODIPY dyes and their derivatives: Syntheses and spectroscopic properties
Aurore Loudet et al.
CHEMICAL REVIEWS (2007)
Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase
Alfredo Ramirez et al.
NATURE GENETICS (2006)
Disruptive effect of chloroquine on lysosomes in cultured rat hepatocytes
A Michihara et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2005)
Vesicle permeabilization by protofibrillar α-synuclein:: Implications for the pathogenesis and treatment of Parkinson's disease
MJ Volles et al.
BIOCHEMISTRY (2001)
Enhanced plasmid DNA transfection with lysosomotropic agents in cultured fibroblasts
K Ciftci et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2001)
A hydrophobic stretch of 12 amino acid residues in the middle of α-synuclein is essential for filament assembly
BI Giasson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
分享论文
