4.6 Article

The hepatokine FGF21 is crucial for peroxisome proliferator-activated receptor-α agonist-induced amelioration of metabolic disorders in obese mice

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Gastroenterology & Hepatology

Hepatocyte-specific PPARA expression exclusively promotes agonist-induced cell proliferation without influence from nonparenchymal cells

Chad N. Brocker et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2017)

Article Endocrinology & Metabolism

Fatty acid metabolism and the basis of brown adipose tissue function

Maria Calderon-Dominguez et al.

ADIPOCYTE (2016)

Article Gastroenterology & Hepatology

Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

Alexandra Montagner et al.

Article Biochemistry & Molecular Biology

Fenofibrate insulates diacylglycerol in lipid droplet/ER and preserves insulin signaling transduction in the liver of high fat fed mice

Stanley M. H. Chan et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)

Review Medicine, Research & Experimental

Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis

Labros Sidossis et al.

JOURNAL OF CLINICAL INVESTIGATION (2015)

Article Medicine, General & Internal

Management of obesity: improvement of health-care training and systems for prevention and care

William H. Dietz et al.

LANCET (2015)

Article Medicine, General & Internal

Patchy progress on obesity prevention: emerging examples, entrenched barriers, and new thinking

Christina A. Roberto et al.

LANCET (2015)

Article Biochemistry & Molecular Biology

Genetic and functional characterization of clonally derived adult human brown adipocytes

Kosaku Shinoda et al.

NATURE MEDICINE (2015)

Article Biochemistry & Molecular Biology

Metabolomics reveal 1-palmitoyl lysophosphatidylcholine production by peroxisome proliferator-activated receptor α

Haruya Takahashi et al.

JOURNAL OF LIPID RESEARCH (2015)

Article Medicine, Research & Experimental

Recruited brown adipose tissue as an antiobesity agent in humans

Takeshi Yoneshiro et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Medicine, Research & Experimental

Cold acclimation recruits human brown fat and increases nonshivering thermogenesis

Anouk A. J. J. van der Lans et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Endocrinology & Metabolism

The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue

Andrew C. Adams et al.

MOLECULAR METABOLISM (2013)

Article Endocrinology & Metabolism

Lack of Overt FGF21 Resistance in Two Mouse Models of Obesity and Insulin Resistance

Clarence Hale et al.

ENDOCRINOLOGY (2012)

Article Cell Biology

FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis

Ffolliott M. Fisher et al.

GENES & DEVELOPMENT (2012)

Article Endocrinology & Metabolism

Farnesol, an isoprenoid, improves metabolic abnormalities in mice via both PPAR α-dependent and -independent pathways

Tsuyoshi Goto et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2011)

Article Biochemistry & Molecular Biology

Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist

Tsuyoshi Goto et al.

BIOCHEMICAL JOURNAL (2011)

Article Nutrition & Dietetics

Mango modulates body fat and plasma glucose and lipids in mice fed a high-fat diet

Edralin A. Lucas et al.

BRITISH JOURNAL OF NUTRITION (2011)

Article Endocrinology & Metabolism

Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity

Fredirick L. Mashili et al.

DIABETES-METABOLISM RESEARCH AND REVIEWS (2011)

Article Biochemistry & Molecular Biology

Thermogenic Activation Induces FGF21 Expression and Release in Brown Adipose Tissue

Elayne Hondares et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Endocrinology & Metabolism

The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation

G. Barbatelli et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2010)

Article Biochemical Research Methods

EBImage-an R package for image processing with applications to cellular phenotypes

Gregoire Pau et al.

BIOINFORMATICS (2010)

Article Endocrinology & Metabolism

Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State

Ffolliott M. Fisher et al.

DIABETES (2010)

Article Medicine, Research & Experimental

Peroxisome Proliferator-Activated Receptor Alpha Target Genes

Maryam Rakhshandehroo et al.

PPAR RESEARCH (2010)

Article Medicine, General & Internal

Cold-Activated Brown Adipose Tissue in Healthy Men

Wouter D. van Marken Lichtenbelt et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Medicine, General & Internal

Identification and Importance of Brown Adipose Tissue in Adult Humans.

Aaron M. Cypess et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Multidisciplinary Sciences

FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

Matthew J. Potthoff et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Endocrinology & Metabolism

Fibroblast Growth Factor 21 Corrects Obesity in Mice

Tamer Coskun et al.

ENDOCRINOLOGY (2008)

Article Endocrinology & Metabolism

βKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c

Masashi Suzuki et al.

MOLECULAR ENDOCRINOLOGY (2008)

Article Pharmacology & Pharmacy

PPARα:: Mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators

Frank J. Gonzalez et al.

TOXICOLOGY (2008)

Article Multidisciplinary Sciences

The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome

Kitt Falk Petersen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

βKlotho is required for metabolic activity of fibroblast growth factor 21

Yasushi Ogawa et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Hematology

Effects of peroxisome proliferator-activated receptor ligands, bezafibrate and fenofibrate, on adiponectin level

Aki Hiuge et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)

Review Pharmacology & Pharmacy

International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors

Liliane Michalik et al.

PHARMACOLOGICAL REVIEWS (2006)

Article Medicine, General & Internal

Attenuation of progression of insulin resistance in patients with coronary artery disease by bezafibrate

A Tenenbaum et al.

ARCHIVES OF INTERNAL MEDICINE (2006)

Article Medicine, Research & Experimental

FGF-21 as a novel metabolic regulator

A Kharitonenkov et al.

JOURNAL OF CLINICAL INVESTIGATION (2005)

Review Biochemistry & Molecular Biology

PPARs and the complex journey to obesity

RM Evans et al.

NATURE MEDICINE (2004)

Article Endocrinology & Metabolism

The biology of mitochondrial uncoupling proteins

S Rousset et al.

DIABETES (2004)

Article Biochemistry & Molecular Biology

Peroxisome proliferator-activated receptor α activators improve insulin sensitivity and reduce adiposity

M Guerre-Millo et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)