期刊
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
卷 31, 期 10, 页码 -出版社
WILEY
DOI: 10.1002/jbt.21956
关键词
-amylase; -glycosidase; enzyme inhibition; phenolic compounds
-Glycosidase is a catalytic enzyme and it destroys the complex carbohydrates into simple absorbable sugar units. The natural phenolic compounds were tested for their antidiabetic properties as -glycosidase and -amylase inhibitors. The phenolic compounds investigated in this study have been used as antidiabetic common medicines. This paper aimed to consider their capability to inhibit -amylase and -glycosidase, two significant enzymes defined in serum glucose adjustment. These examination recorded impressive inhibition profiles with IC50 values in the range of 137.36-737.23nM against -amylase and 29.01-157.96nM against -glycosidase.
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