期刊
JOURNAL OF APPLIED PHYSIOLOGY
卷 122, 期 5, 页码 1077-1087出版社
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/japplphysiol.00622.2016
关键词
open window; repeated exercise bouts; immunodepression; overreaching; sleep
资金
- Centre of Excellence for Applied Sport Science Research at the Queensland Academy of Sport, Brisbane, Queensland, Australia
Peake JM, Neubauer O, Walsh NP, Simpson RJ. Recovery of the immune system after exercise. J Appl Physiol 122: 1077-1087, 2017. First published December 1, 2016; doi: 10.1152/japplphysiol.00622.2016.-The notion that prolonged, intense exercise causes an open window of immunodepression during recovery after exercise is well accepted. Repeated exercise bouts or intensified training without sufficient recovery may increase the risk of illness. However, except for salivary IgA, clear and consistent markers of this immunodepression remain elusive. Exercise increases circulating neutrophil and monocyte counts and reduces circulating lymphocyte count during recovery. This lymphopenia results from preferential egress of lymphocyte subtypes with potent effector functions [e.g., natural killer (NK) cells, gamma delta T cells, and CD8(+) T cells]. These lymphocytes most likely translocate to peripheral sites of potential antigen encounter (e.g., lungs and gut). This redeployment of effector lymphocytes is an integral part of the physiological stress response to exercise. Current knowledge about changes in immune function during recovery from exercise is derived from assessment at the cell population level of isolated cells ex vivo or in blood. This assessment can be biased by large changes in the distribution of immune cells between blood and peripheral tissues during and after exercise. Some evidence suggests that reduced immune cell function in vitro may coincide with changes in vivo and rates of illness after exercise, but more work is required to substantiate this notion. Among the various nutritional strategies and physical therapies that athletes use to recover from exercise, carbohydrate supplementation is the most effective for minimizing immune disturbances during exercise recovery. Sleep is an important aspect of recovery, but more research is needed to determine how sleep disruption influences the immune system of athletes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据