4.6 Article

Synthesis of hierarchically mesoporous silica with encapsulated avobenzone as a UV protection filter

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RSC ADVANCES
卷 10, 期 27, 页码 15846-15852

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ROYAL SOC CHEMISTRY
DOI: 10.1039/d0ra01837f

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资金

  1. Research Project of Ministry of Science and Technology, Taiwan [MOST 107-2221-E-037-001-MY3]
  2. Research Cooperation Project of Kaohsiung Medical University [108-CCH-KMU-007]
  3. Changhua Christian Hospital, Changhua Christian Medical Foundation, Taiwan [108-CCH-KMU-007]

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In this study, hierarchically mesoporous silica (HMS) with properties such as high specific surface area, high photostability, and no cellular toxicity was synthesized. The synthesized silica can be considered as an excellent carrier candidate material. Through the use of nitrogen adsorption and desorption analysis, the shape of the hysteresis loop implied the presence of mesoporous structures in the HMS powder. In addition, the encapsulation efficiency was more than 90%. These results showed that avobenzone could be encapsulated into the HMS powder because of its high specific surface area and pore volume. Additionally, X-ray diffractometry (XRD), Fourier transform infrared spectroscopy (FTIR), thermal gravimetric analysis (TGA), and UV-visible (Vis) spectrophotometry were used to prove that the hierarchically mesoporous silica was able to effectively encapsulate avobenzone. In addition, the new synthetic sunscreen kept its excellent UVA absorption properties after being encapsulated.

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