4.7 Article

A label-free homogeneous electrochemical cytosensor for the ultrasensitive detection of cancer cells based on multiaptamer-functionalized DNA tetrahedral nanostructures

期刊

CHEMICAL COMMUNICATIONS
卷 56, 期 27, 页码 3883-3886

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ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc00788a

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资金

  1. National Natural Science Foundation of China [21804077, 21605092, 21775082]
  2. Shandong Province Higher Educational Program for Young Innovation Talents
  3. Special Foundation for Distinguished Taishan Scholar of Shandong Province [ts201511052]
  4. Research Foundation for Distinguished Scholars of Qingdao Agricultural University [665-1119006]

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We developed a label-free homogeneous electrochemical cytosensor for ultrasensitive detection of cancer cells based on multiaptamer-functionalized DNA tetrahedral nanostructures, which avoided expensive labeling and sophisticated immobilization procedures, providing opportunities for precisely detecting cancer cells in clinical applications.

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