期刊
BRITISH JOURNAL OF PAIN
卷 14, 期 2, 页码 133-140出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/2049463720914332
关键词
Neuropathic pain; capsaicin
资金
- Chelsea and Westminster Healthcare National Health Service (NHS) Foundation Trust
Capsaicin, derived from the chilli pepper plant, is available in high concentration (8%) patches to provide topical therapy for neuropathic pain. Its analgesic effects relate to defunctionalisation and nerve terminal retraction of predominantly C fibres in the dermis and epidermis. Systematic reviews and meta-analysis support its use for the management of post-herpetic neuralgia and HIV neuropathy with some evidence for use in painful peripheral diabetic neuropathy. The article concludes with advice on the practicalities of running a topical 8% capsaicin clinic for peripheral neuropathic pain.
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