4.7 Article

Oxyanion transport across lipid bilayers: direct measurements in large and giant unilamellar vesicles

期刊

CHEMICAL COMMUNICATIONS
卷 56, 期 36, 页码 4910-4913

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ROYAL SOC CHEMISTRY
DOI: 10.1039/C9CC09888G

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资金

  1. National Science Centre, Poland (OPUS grant) [2018/31/B/ST5/02085]
  2. Netherlands Organisation of Scientific Research (VICI grant) [724.014.001]
  3. European Union through the European Regional Development Fund under the Operational Programme Innovative Economy 2007-2013

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A simple di(thioamido)carbazole 1 serves as a potent multispecific transporter for various biologically relevant oxyanions, such as drugs, metabolites and model organic phosphate. The transport kinetics of a wide range of oxyanions can be easily quantified by a modified lucigenin assay in both large and giant unilamellar vesicles.

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