期刊
CURRENT TOPICS IN MEDICINAL CHEMISTRY
卷 16, 期 3, 页码 281-290出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1568026615666150701114527
关键词
Nanomaterials; Peptide; Regenerative medicine; Self-assembly; Targeted delivery system
资金
- National Natural Science Foundation of China [81471777, 81102409, 81372579]
- Department of Science and Technology of Hunan Province [2014GK3082]
- Natural Science Foundation of Hunan province [13JJ6096]
- University of South China [NHCXTD05]
- Young Talent Program of the University of South China
- Health Department of Hunan Province 225 Talent Project
Self-assembled peptide nanomaterials display the advantageous properties of injectability, biodegradability and biocompatibility. These peptide nanomaterials, by self-assembling, can be widely applied in such fields as drug delivery (small molecules and large molecules), regenerative medicine and nanobiotechnology. In this review, we mainly discuss the properties of these peptide nanomaterials in their physical, chemical and biological aspects. Also discussed are recent advances in their potential applications as drug delivery systems and for uses in regenerative medicine. These current advances show a bright future for the development and clinical applications of self-assembled peptide-based nanotechnology and nanomedicine. However, there are still some big challenges for us to face before these peptide nanomaterials eventually can be used for the treatment of human diseases.
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