期刊
ISCIENCE
卷 23, 期 4, 页码 -出版社
CELL PRESS
DOI: 10.1016/j.isci.2020.101041
关键词
-
资金
- National Natural Sciences Foundation of China [31871046, 91632107, 91232720, 91632112, 31800867]
- Chinese Academy of Sciences [XDB02040002, QYZDY-SSW-SMC015]
- Ministry of Science and Technology of China [2012CB825504]
Many animals perceive features of higher-order visual motion that are beyond the spatiotemporal correlations of luminance defined in first-order motion. Although the neural mechanisms of first-order motion detection have become understood in recent years, those underlying higher-order motion perception remain unclear. Here, we established a paradigm to assess the detection of theta motion-a type of higher-order motion-in freely walking Drosophila. Behavioral screening using this paradigm identified two clusters of neurons in the central brain, designated as R18C12, which were required for perception of theta motion but not for first-order motion. Furthermore, theta motion-activated R18C12 neurons were structurally and functionally located downstream of visual projection neurons in lobula, lobula columnar cells LC16, which activated R18C12 neurons via interactions of acetylcholine (ACh) and muscarinic acetylcholine receptors (mAChRs). The current study provides new insights into LC neurons and the neuronal mechanisms underlying visual information processing in complex natural scenes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据