4.0 Article

Influence of Body Mass Index ≥30 on Pure Laparoscopic Donor Right Hepatectomy

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ANNALS OF TRANSPLANTATION
卷 25, 期 -, 页码 -

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INT SCIENTIFIC INFORMATION, INC
DOI: 10.12659/AOT.923094

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Hepatectomy; Laparoscopy; Liver Transplantation; Living Donors; Obesity

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Background: Pure laparoscopic donor right hepatectomy (PLDRH) for donors with obesity has not been previously investigated. This study aimed to investigate the influence of donor obesity (BMI >= 30 kg/m(2)) on and clinical outcomes after PLDRH. Material/Methods: Records of all living donors who underwent PLDRH between November 2015 and May 2018 and open conventional donor right hepatectomy (CDRH) between January 2011 and October 2015 at Seoul National University Hospital were retrospectively reviewed. The donors were divided into 3 groups: PLDRH BMI >= 30, PLDRH BMI <30, and CDRH BMI >= 30. Results: Donors in the PLDRH BMI >= 30 group (n=7) were compared with those in the PLDRH BMI <30 (n=65; control 1) and CDRH BMI >= 30 (n=8; control 2) groups. Graft weight was significantly heavier in PLDRH BMI >= 30 than in control 1 (P=0.012). The lowest hemoglobin (Hb) value was higher (P=0.014) and Delta Hb% was lower (P=0.005) in PLDRH BMI >= 30 than in control 1. Similarly, the lowest Hb value was higher (P=0.021) and Delta Hb% was lower (P<0.001) in PLDRH BMI >= 30 than in control 2. The peak alanine aminotransferase (ALT) (P=0.029) and Delta ALT% were higher in PLDRH BMI >= 30 than in control 2. No significant differences in hospital stay and postoperative complications were found between PLDRH BMI and control 1, as well as between PLDRH BMI >= 30 and control 2. Conclusions: This study revealed that PLDRH is feasible in donors with obesity.

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