期刊
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
卷 67, 期 3, 页码 151-160出版社
TAYLOR & FRANCIS AS
DOI: 10.1080/00914037.2017.1309542
关键词
Anti-inflammatory; antioxidant properties; lemon fiber; polycaprolactone; tyrosinase activities
资金
- Ministry of Science and Technology (Taipei City, Taiwan, R.O.C.) [MOST-104-2221-E-244-011-]
The structure, cytocompatibility, and biological activity of composites prepared from polycaprolactone (PCL) and lemon fiber (LF) blends (PCL/LF) were evaluated. Acrylic acid-grafted PCL (PCL-g-AA) was used to enhance the desirable characteristics of these composites, which had better tensile properties than the corresponding PCL/LF composites. A cytocompatibility evaluation with normal human foreskin fibroblasts of the water released from the PCL/LF and PCL-g-AA/LF composites indicated that both materials were nontoxic. Moreover, LF enhanced the flavonoid and polyphenol contents and the anti-inflammatory and antioxidant properties of the PCL-g-AA/LF and PCL/LF composites. We analyzed the effects of these composites in mushroom tyrosinase activity and B16-F10 melanoma cells; the PCL/LF and PCL-g-AA/LF membranes demonstrated reduced tyrosinase activity. Composites of PCL-g-AA or PCL containing LF had better antibacterial activity.
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