相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The functional roles of PML nuclear bodies in genome maintenance
Hae Ryung Chang et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2018)
Inherited DNA lesions determine G1 duration in the next cell cycle
Aleksandra Lezaja et al.
CELL CYCLE (2018)
The FEN1 L209P mutation interferes with long-patch base excision repair and induces cellular transformation
H. Sun et al.
ONCOGENE (2017)
Perturbations in the Replication Program Contribute to Genomic Instability in Cancer
Britny Blumenfeld et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis
Stefano Di Marco et al.
MOLECULAR CELL (2017)
Replication stress, DNA damage signalling, and cytomegalovirus infection in human medulloblastomas
Jiri Bartek et al.
MOLECULAR ONCOLOGY (2017)
Regulation of repair pathway choice at two-ended DNA double-strand breaks
Atsushi Shibata
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2017)
The control of DNA repair by the cell cycle
Nicole Hustedt et al.
NATURE CELL BIOLOGY (2017)
Mechanisms of DNA-protein crosslink repair
Julian Stingele et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
Genome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes
Francois Aymard et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
CTCF prevents genomic instability by promoting homologous recombination-directed DNA double-strand break repair
Fengchao Lang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
BRCA2 suppresses replication stress-induced mitotic and G1 abnormalities through homologous recombination
Weiran Feng et al.
NATURE COMMUNICATIONS (2017)
DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression
Alexis R. Barr et al.
NATURE COMMUNICATIONS (2017)
MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells
Xianning Lai et al.
NATURE COMMUNICATIONS (2017)
Genome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes
Francois Aymard et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Endogenous Replication Stress in Mother Cells Leads to Quiescence of Daughter Cells
Mansi Arora et al.
CELL REPORTS (2017)
BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation
Mayu Isono et al.
CELL REPORTS (2017)
Replication-Coupled Dilution of H4K20me2 Guides 53BP1 to Pre-replicative Chromatin
Stefania Pellegrino et al.
CELL REPORTS (2017)
5-hydroxymethylcytosine in DNA repair: A new player or a red herring?
Omar L. Kantidze et al.
CELL CYCLE (2017)
Differential effect of the overexpression of Rad2/XPG family endonucleases on genome integrity in yeast and human cells
Sonia Jimeno et al.
DNA REPAIR (2017)
Residual Cdk1/2 activity after DNA damage promotes senescence
Erik Mullers et al.
AGING CELL (2017)
Nuclear bodies: news insights into structure and function
David Stanek et al.
CURRENT OPINION IN CELL BIOLOGY (2017)
Rescue from replication stress during mitosis
Michalis Fragkos et al.
CELL CYCLE (2017)
A novel single-cell method provides direct evidence of persistent DNA damage in senescent cells and aged mammalian tissues
Alessandro Galbiati et al.
AGING CELL (2017)
ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells
Marwan Kwok et al.
BLOOD (2016)
Conflict Resolution in the Genome: How Transcription and Replication Make It Work
Stephan Hamperl et al.
CELL (2016)
Localized Movement and Levels of 53BP1 Protein Are Changed by γ-irradiation in PML Deficient Cells
Sona Legartova et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2016)
DEAD Box 1 Facilitates Removal of RNA and Homologous Recombination at DNA Double-Strand Breaks
Lei Li et al.
MOLECULAR AND CELLULAR BIOLOGY (2016)
Epigenome Maintenance in Response to DNA Damage
Juliette Dabin et al.
MOLECULAR CELL (2016)
RAD52 Facilitates Mitotic DNA Synthesis Following Replication Stress
Rahul Bhowmick et al.
MOLECULAR CELL (2016)
Activation of the ATR kinase by the RPA-binding protein ETAA1
Peter Haahr et al.
NATURE CELL BIOLOGY (2016)
Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells
Alberto Moreno et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells
Akshay K. Ahuja et al.
NATURE COMMUNICATIONS (2016)
Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA
Emmanuelle Despras et al.
NATURE COMMUNICATIONS (2016)
Increased global transcription activity as a mechanism of replication stress in cancer
Panagiotis Kotsantis et al.
NATURE COMMUNICATIONS (2016)
BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity
Rikke D. Rasmussen et al.
NATURE COMMUNICATIONS (2016)
Profiling DNA damage response following mitotic perturbations
Ronni S. Pedersen et al.
NATURE COMMUNICATIONS (2016)
5-Hydroxymethylcytosine Marks Sites of DNA Damage and Promotes Genome Stability
Georgia Rose Kafer et al.
CELL REPORTS (2016)
被撤回的出版物: USP1 Regulates Cellular Senescence by Controlling Genomic Integrity (Retracted article. See vol. 34, 2021)
Muege Ogrunc et al.
CELL REPORTS (2016)
Cyclin Kinase-independent role of p21cDKN1A in the promotion of nascent DNA elongation in unstressed cells
Sabrina F. Mansilla et al.
ELIFE (2016)
The Cell Killing Mechanisms of Hydroxyurea
Amanpreet Singh et al.
GENES (2016)
DNA Replication Stress as a Hallmark of Cancer
Morgane Macheret et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 10 (2015)
Myc induced replicative stress response: How to cope with it and exploit it
Sara Rohban et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2015)
Rif1 Is Required for Resolution of Ultrafine DNA Bridges in Anaphase to Ensure Genomic Stability
Rutger C. C. Hengeveld et al.
DEVELOPMENTAL CELL (2015)
TopBP1 is required at mitosis to reduce transmission of DNA damage to G1 daughter cells
Rune Troelsgaard Pedersen et al.
JOURNAL OF CELL BIOLOGY (2015)
ATR and a Chk1-Aurora B pathway coordinate postmitotic genome surveillance with cytokinetic abscission
Douglas R. Mackay et al.
MOLECULAR BIOLOGY OF THE CELL (2015)
The SLX4 Complex Is a SUMO E3 Ligase that Impacts on Replication Stress Outcome and Genome Stability
Jean-Hugues Guervilly et al.
MOLECULAR CELL (2015)
Noncovalent Interactions with SUMO and Ubiquitin Orchestrate Distinct Functions of the SLX4 Complex in Genome Maintenance
Jian Ouyang et al.
MOLECULAR CELL (2015)
BOD1L Is Required to Suppress Deleterious Resection of Stressed Replication Forks
Martin R. Higgs et al.
MOLECULAR CELL (2015)
BRCA1 Recruitment to Transcriptional Pause Sites Is Required for R-Loop-Driven DNA Damage Repair
Elodie Hatchi et al.
MOLECULAR CELL (2015)
Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage
Tina Thorslund et al.
NATURE (2015)
Replication stress activates DNA repair synthesis in mitosis
Sheroy Minocherhomji et al.
NATURE (2015)
Replication fork integrity and intra-S phase checkpoint suppress gene amplification
Anna Kondratova et al.
NUCLEIC ACIDS RESEARCH (2015)
Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart
Kumar Somyajit et al.
NUCLEIC ACIDS RESEARCH (2015)
Human RecQ Helicases in DNA Repair, Recombination, and Replication
Deborah L. Croteau et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 83 (2014)
Are common fragile sites merely structural domains or highly organized functional'' units susceptible to oncogenic stress?
Alexandros G. Georgakilas et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2014)
Updating the mechanisms of common fragile site instability: how to reconcile the different views?
Benoit Le Tallec et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2014)
TopBP1: A BRCT-scaffold protein functioning in multiple cellular pathways
Christopher P. Wardlaw et al.
DNA REPAIR (2014)
ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress
Luisa Schmidt et al.
DNA REPAIR (2014)
DNA replication stress: Causes, resolution and disease
Abdelghani Mazouzi et al.
EXPERIMENTAL CELL RESEARCH (2014)
Roles of SLX1-SLX4, MUS81-EME1, and GEN1 in avoiding genome instability and mitotic catastrophe
Shriparna Sarbajna et al.
GENES & DEVELOPMENT (2014)
53BP1, BRCA1, and the Choice between Recombination and End Joining at DNA Double-Strand Breaks
James M. Daley et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
Dephosphorylation Enables the Recruitment of 53BP1 to Double-Strand DNA Breaks
Dong-Hyun Lee et al.
MOLECULAR CELL (2014)
Causes and consequences of replication stress
Michelle K. Zeman et al.
NATURE CELL BIOLOGY (2014)
A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression
Spencer W. Luebben et al.
NUCLEIC ACIDS RESEARCH (2014)
Basal p21 controls population heterogeneity in cycling and quiescent cell cycle states
K. Wesley Overton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Mitosis Inhibits DNA Double-Strand Break Repair to Guard Against Telomere Fusions
Alexandre Orthwein et al.
SCIENCE (2014)
The causes of replication stress and their consequences on genome stability and cell fate
Indiana Magdalou et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2014)
Spartan deficiency causes genomic instability and progeroid phenotypes
Reeja S. Maskey et al.
NATURE COMMUNICATIONS (2014)
The Proliferation-Quiescence Decision Is Controlled by a Bifurcation in CDK2 Activity at Mitotic Exit
Sabrina L. Spencer et al.
CELL (2013)
Downregulation of Wip1 phosphatase modulates the cellular threshold of DNA damage signaling in mitosis
Libor Macurek et al.
CELL CYCLE (2013)
DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation
Remy Betous et al.
EMBO JOURNAL (2013)
DNA-damage response in chromatin of ribosomal genes and the surrounding genome
Veronika Foltankova et al.
GENE (2013)
DNA synthesis by Pol η promotes fragile site stability by preventing under-replicated DNA in mitosis
Valerie Bergoglio et al.
JOURNAL OF CELL BIOLOGY (2013)
Mechanism of Replicative DNA Polymerase Delta Pausing and a Potential Role for DNA Polymerase Kappa in Common Fragile Site Replication
Erin Walsh et al.
JOURNAL OF MOLECULAR BIOLOGY (2013)
Senataxin, Defective in the Neurodegenerative Disorder Ataxia with Oculomotor Apraxia 2, Lies at the Interface of Transcription and the DNA Damage Response
Oezlem Yuece et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
Coordinated Actions of SLX1-SLX4 and MUS81-EME1 for Holliday Junction Resolution in Human Cells
Haley D. M. Wyatt et al.
MOLECULAR CELL (2013)
A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice
Cristina Escribano-Diaz et al.
MOLECULAR CELL (2013)
Replication stress links structural and numerical cancer chromosomal instability
Rebecca A. Burrell et al.
NATURE (2013)
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark
Amelie Fradet-Turcotte et al.
NATURE (2013)
ERCC1 and MUS81-EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis
Valeria Naim et al.
NATURE CELL BIOLOGY (2013)
MUS81 promotes common fragile site expression
Songmin Ying et al.
NATURE CELL BIOLOGY (2013)
Rev3, the catalytic subunit of Polζ, is required for maintaining fragile site stability in human cells
Audesh Bhat et al.
NUCLEIC ACIDS RESEARCH (2013)
HP1 promotes tumor suppressor BRCA1 functions during the DNA damage response
Young-Ho Lee et al.
NUCLEIC ACIDS RESEARCH (2013)
Helq acts in parallel to Fancc to suppress replication-associated genome instability
Spencer W. Luebben et al.
NUCLEIC ACIDS RESEARCH (2013)
A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2
Katharina Schlacher et al.
CANCER CELL (2012)
RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling
Francesca Mattiroli et al.
CELL (2012)
TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes
Thorkell Gudjonsson et al.
CELL (2012)
Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1
P. Moudry et al.
CELL DEATH AND DIFFERENTIATION (2012)
Dysregulation of DNA polymerase κ recruitment to replication forks results in genomic instability
Mathew J. K. Jones et al.
EMBO JOURNAL (2012)
The DNA translocase activity of FANCM protects stalled replication forks
Andrew N. Blackford et al.
HUMAN MOLECULAR GENETICS (2012)
Cyclin-Dependent Kinase Suppression by WEE1 Kinase Protects the Genome through Control of Replication Initiation and Nucleotide Consumption
Halfdan Beck et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response
Petra Beli et al.
MOLECULAR CELL (2012)
DNA polymerase zeta is required for proliferation of normal mammalian cells
Sabine S. Lange et al.
NUCLEIC ACIDS RESEARCH (2012)
SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response
Andreas Mund et al.
NUCLEIC ACIDS RESEARCH (2012)
Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11
Katharina Schlacher et al.
CELL (2011)
Significance of p53-binding protein 1 nuclear foci in uterine cervical lesions: endogenous DNA double strand breaks and genomic instability during carcinogenesis
Katsuya Matsuda et al.
HISTOPATHOLOGY (2011)
Replication stress induces 53BP1-containing OPT domains in G1 cells
Jeanine A. Harrigan et al.
JOURNAL OF CELL BIOLOGY (2011)
DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion
Francis Rodier et al.
JOURNAL OF CELL SCIENCE (2011)
Nucleation of nuclear bodies by RNA
Sergey P. Shevtsov et al.
NATURE CELL BIOLOGY (2011)
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress
Claudia Lukas et al.
NATURE CELL BIOLOGY (2011)
Biogenesis and function of nuclear bodies
Yuntao S. Mao et al.
TRENDS IN GENETICS (2011)
ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks
Niraj M. Shanbhag et al.
CELL (2010)
TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint
Rachele Cescutti et al.
EMBO JOURNAL (2010)
DNA damage signaling in response to double-strand breaks during mitosis
Simona Giunta et al.
JOURNAL OF CELL BIOLOGY (2010)
Genomic instability - an evolving hallmark of cancer
Simona Negrini et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Analysis of DNA double-strand break response and chromatin structure in mitosis using laser microirradiation
Veronica Gomez-Godinez et al.
NUCLEIC ACIDS RESEARCH (2010)
Replication stress and oxidative damage contribute to aberrant constitutive activation of DNA damage signalling in human gliomas
J. Bartkova et al.
ONCOGENE (2010)
Targeting the Mitotic Checkpoint to Kill Tumor Cells
Aniek Janssen et al.
Hormones & Cancer (2010)
On the origins of ultra-fine anaphase bridges
Kok Lung Chan et al.
CELL CYCLE (2009)
Replication stress induces sister-chromatid bridging at fragile site loci in mitosis
Kok Lung Chan et al.
NATURE CELL BIOLOGY (2009)
The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities
Valeria Naim et al.
NATURE CELL BIOLOGY (2009)
A role for DEAD box 1 at DNA double-strand breaks
Lei Li et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
DNA damage, cellular senescence and organismal ageing: causal or correlative?
Jian-Hua Chen et al.
NUCLEIC ACIDS RESEARCH (2007)
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
Niels Mailand et al.
CELL (2007)
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
Shuhei Matsuoka et al.
SCIENCE (2007)
RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites
Bijan Sobhian et al.
SCIENCE (2007)
Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair
Maria Victoria Botuyan et al.
CELL (2006)
Promyelocytic leukemia nuclear bodies behave as DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1 and the kinases ATM, Chk2, and ATR
Graham Dellaire et al.
JOURNAL OF CELL BIOLOGY (2006)
Dynamic nature of cleavage bodies and their spatial relationship to DDX1 bodies, Cajal bodies, and gems
L Li et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
M Stucki et al.
CELL (2005)
Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1
S Bekker-Jensen et al.
JOURNAL OF CELL BIOLOGY (2005)
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
VG Gorgoulis et al.
NATURE (2005)
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
J Falck et al.
NATURE (2005)
A DNA damage checkpoint response in telomere-initiated senescence
FD di Fagagna et al.
NATURE (2003)
Requirement of the MRN complex for ATM activation by DNA damage
T Uziel et al.
EMBO JOURNAL (2003)
DNA damage foci at dysfunctional telomeres
H Takai et al.
CURRENT BIOLOGY (2003)
p53 binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice
IM Ward et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
The role of PML in tumor suppression
P Salomoni et al.
CELL (2002)
p53 Binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
LB Schultz et al.
JOURNAL OF CELL BIOLOGY (2000)
The function of PML in p53-dependent apoptosis
A Guo et al.
NATURE CELL BIOLOGY (2000)
分享论文
