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Chengkai Dai et al.
CELL (2007)
Selective suppression of lymphomas by functional loss of Hsf1 in a p53-deficient mouse model for spontaneous tumors
J-N Min et al.
ONCOGENE (2007)
Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer
Anna Rodina et al.
NATURE CHEMICAL BIOLOGY (2007)
A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib
Thibault de la Motte Rouge et al.
CANCER RESEARCH (2007)
Evaluation of renal cell carcinoma vaccines targeting carbonic anhydrase IX using heat shock protein 110
Hyung L. Kim et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2007)
Contribution of oncoproteomics to cancer biomarker discovery
William C. S. Cho
MOLECULAR CANCER (2007)
Lens epithelium-derived growth factor is an Hsp70-2 regulated guardian of lysosomal stability in human cancer
Mads Daugaard et al.
CANCER RESEARCH (2007)
High levels of heat shock protein Hsp72 in cancer cells suppress default senescence pathways
Julia A. Yaglom et al.
CANCER RESEARCH (2007)
Molecular chaperones: Multiple functions, pathologies, and potential applications
Alberto J. L. Macario et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2007)
Hsp27 knockdown using nucleotide-based therapies inhibit tumor growth and enhance chemotherapy in human bladder cancer cells
Masayuki Kamada et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Hsp105 family proteins suppress staurosporine-induced apoptosis by inhibiting the translocation of Bax to mitochondria in HeLa cells
Nobuyuki Yamagishi et al.
EXPERIMENTAL CELL RESEARCH (2006)
(-)-epigallocatechin gallate overcomes resistance to etoposide-induced cell death by targeting the molecular chaperone glucose-regulated protein 78
Svetlana P. Ermakova et al.
CANCER RESEARCH (2006)
Synthetic small interfering RNA targeting heat shock protein 105 induces apoptosis of various cancer cells both in vitro and in vivo
Seiji Hosaka et al.
CANCER SCIENCE (2006)
Glucose regulated proteins in cancer progression, drug resistance and immunotherapy
Yong Fu et al.
CANCER BIOLOGY & THERAPY (2006)
A new tumor suppressor DnaJ-Iike heat shock protein, HLJ1, and survival of patients with non-small-cell lung carcinoma
Meng-Feng Tsai et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2006)
MAPKAPK2 and HSP27 are downstream effectors of p38MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer
L. Xu et al.
ONCOGENE (2006)
Triptolide, an inhibitor of the human heat shock response that enhances stress-induced cell death
SD Westerheide et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Immunoadjuvant chaperone, GRP170, induces 'danger signals' upon interaction with dendritic cells
MH Manjili et al.
IMMUNOLOGY AND CELL BIOLOGY (2006)
Self-association and chaperone activity of Hsp27 are thermally activated
B Lelj-Garolla et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Ha-rasval12 induces HSP70b transcription via the HSE/HSF1 system, but HSP70b expression is suppressed in Ha-rasval12-transformed cells
A Stanhill et al.
ONCOGENE (2006)
Using natural product inhibitors to validate Hsp90 as a molecular target in cancer
Len Neckers
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2006)
Heat shock proteins as vaccine adjuvants in infections and cancer
Brahm H. Segal et al.
DRUG DISCOVERY TODAY (2006)
Immunohistochemical evaluation of heat shock proteins in normal and preinvasive lesions of the cervix
PE Castle et al.
CANCER LETTERS (2005)
Hsp70 inhibits heat-induced apoptosis upstream of mitochondria by preventing Bax translocation
AR Stankiewicz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Tid1 negatively regulates the migratory potential of cancer cells by inhibiting the production of interieukin-8
SW Kim et al.
CANCER RESEARCH (2005)
Expression of heat-shock proteins is associated with major adverse prognostic factors in acute myeloid leukemia
X Thomas et al.
LEUKEMIA RESEARCH (2005)
Phase I pharmacokinetic and pharmacodynarnic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies
U Banerji et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
The transcriptional factor YY1 upregulates the novel invasion suppressor HLJ1 expression and inhibits cancer cell invasion
CC Wang et al.
ONCOGENE (2005)
Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications
DR Ciocca et al.
CELL STRESS & CHAPERONES (2005)
Tid-1 interacts with the von Hippel-Lindau protein and modulates angiogenesis by destabilization of HIF-1α
MK Bae et al.
CANCER RESEARCH (2005)
Mechanistic role of heat shock protein 70 in Bcr-Abl-mediated resistance to apoptosis in human acute leukemia cells
F Guo et al.
BLOOD (2005)
Molecular mechanism of hTid-1, the human homolog of Drosophila tumor suppressor l(2)Tid, in the regulation of NF-kappa B activity and suppression of tumor growth
H Cheng et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Molecular chaperones and the stress of oncogenesis
DD Mosser et al.
ONCOGENE (2004)
Combinatorial attack on multistep oncogenesis by inhibiting the Hsp90 molecular chaperone
P Workman
CANCER LETTERS (2004)
Hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria
T Gotoh et al.
CELL DEATH AND DIFFERENTIATION (2004)
Apg-2 has a chaperone-like activity similar to Hsp110 and is overexpressed in hepatocellular carcinomas
K Gotoh et al.
FEBS LETTERS (2004)
A simple method to cure established tumors by inflammatory killing of normal cells
GA Daniels et al.
NATURE BIOTECHNOLOGY (2004)
Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization
J Nylandsted et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Targeting multiple signal transduction pathways through inhibition of Hsp90
H Zhang et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2004)
Effects of a heat shock protein inhibitor KNK437 on heat sensitivity and heat tolerance in human squamous cell carcinoma cell lines differing in p53 status
K Ohnishi et al.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2004)
Detection of oligomerisation and substrate recognition sites of small heat shock proteins by peptide arrays
N Lentze et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Expression of a dominant negative heat shock factor-1 construct inhibits aneuploidy in prostate carcinoma cells
YQ Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Protein expression profiles in adenocarcinomas and squamous cell carcinomas of the lung generated using tissue microarrays
R Ullmann et al.
JOURNAL OF PATHOLOGY (2004)
Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin
CD Austin et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Heat shock protein 70 promotes cancer cell viability by safeguarding lysosomal integrity
M Gyrd-Hansen et al.
CELL CYCLE (2004)
Depletion of physiological levels of the human TID1 protein renders cancer cell lines resistant to apoptosis mediated by multiple exogenous stimuli
KM Edwards et al.
ONCOGENE (2004)
'The stress of ding': the role of heat shock proteins in the regulation of apoptosis
HM Beere
JOURNAL OF CELL SCIENCE (2004)
Tid1, the human homologue of a Drosophila tumor suppressor, reduces the malignant activity of ErbB-2 in carcinoma cells
SW Kim et al.
CANCER RESEARCH (2004)
Treatment of colon and lung cancer patients with ex vivo heat shock protein 70-peptide-activated, autologous natural killer cells:: a clinical phase I trial
SW Krause et al.
CLINICAL CANCER RESEARCH (2004)
Hsp90: the vulnerable chaperone
G Chiosis et al.
DRUG DISCOVERY TODAY (2004)
HSP110-HER2/neu chaperone complex vaccine induces protective immunity against spontaneous mammary tumors in HER-2/neu transgenic mice
MH Manjili et al.
JOURNAL OF IMMUNOLOGY (2003)
Expression of heat shock protein (Hsp) 70 and Hsp 40 in gastric cancer
H Isomoto et al.
CANCER LETTERS (2003)
Inactivation of dual-specificity phosphatases is involved in the regulation of extracellular signal-regulated kinases by heat shock and hsp72
J Yaglom et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
3′ sulfogalactolipid binding specifically inhibits Hsp70 ATPase activity in vitro
H Whetstone et al.
BIOCHEMISTRY (2003)
Development of Radicicol Analogues
Shiro Soga et al.
CURRENT CANCER DRUG TARGETS (2003)
Expression of heat shock protein (Hsp) 70 and Hsp 40 in colorectal cancer
Y Kanazawa et al.
MEDICAL ONCOLOGY (2003)
The anti-apoptotic function of Hsp70 in the interferon-inducible double-stranded RNA-dependent protein kinase-mediated death signaling pathway requires the Fanconi anemia protein, FANCC
QS Pang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Hsp27 as a negative regulator of cytochrome c release
C Paul et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Role of hsp105 in protection against stress-induced apoptosis in neuronal PC12 cells
T Hatayama et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Heat-shock protein 70 antagonizes apoptosis-inducing factor
L Ravagnan et al.
NATURE CELL BIOLOGY (2001)
Identification of novel markers for monitoring minimal residual disease in acute lymphoblastic leukemia
JS Chen et al.
BLOOD (2001)
Autoantibody to heat shock protein Hsp40 in sera of lung cancer patients
MI Oka et al.
JAPANESE JOURNAL OF CANCER RESEARCH (2001)
Role of the heat shock response and molecular chaperones in oncogenesis and cell death
C Jolly et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2000)
Hsp27 negatively regulates cell death by interacting with cytochrome c
JM Bruey et al.
NATURE CELL BIOLOGY (2000)
Negative regulation of the Apaf-1 apoptosome by Hsp70
A Saleh et al.
NATURE CELL BIOLOGY (2000)
Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2
J Nylandsted et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
A novel association between the human heat shock transcription factor 1 (HSF1) and prostate adenocarcinoma
AT Hoang et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
Flavonoids suppress androgen-independent human prostate tumor proliferation
LM Knowles et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2000)
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