期刊
CURRENT OPINION IN PHYSIOLOGY
卷 15, 期 -, 页码 143-151出版社
ELSEVIER
DOI: 10.1016/j.cophys.2019.12.012
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类别
资金
- National Institutes of Health [R00MH103399, R21NS106345]
- Coin for Alzheimer's Research Trust (CART)
- Citizens United for Research in Epilepsy (CURE)
Sleep-wake control is dependent upon multiple brain areas widely distributed throughout the neural axis. Historically, the monoaminergic and cholinergic neurons of the ascending arousal system were the first to be discovered, and it was only relatively recently that GABAergic and glutamatergic wake-promoting and sleep-promoting populations have been identified. Contemporary advances in molecular-genetic tools have revealed both the complexity and heterogeneity of GABAergic NREM sleep-promoting neurons as well as REM sleep-regulating populations in the brainstem such as glutamatergic neurons in the sublaterodorsal nucleus.
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