相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。The Role of PAR2 in TGF-β1-Induced ERK Activation and Cell Motility
Hendrik Ungefroren et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Transforming Growth Factor-β1/Activin Receptor-like Kinase 5-Mediated Cell Migration is Dependent on the Protein Proteinase-Activated Receptor 2 but not on Proteinase-Activated Receptor 2-Stimulated Gq-Calcium Signalingle
Hendrik Ungefroren et al.
MOLECULAR PHARMACOLOGY (2017)
Structural insight into allosteric modulation of protease-activated receptor 2
Robert K. Y. Cheng et al.
NATURE (2017)
Release of endothelial cell associated VEGFR2 during TGF-β modulated angiogenesis in vitro
M. Jarad et al.
BMC CELL BIOLOGY (2017)
Extracellular vesicles from malignant effusions induce tumor cell migration: inhibitory effect of LMWH tinzaparin
Hans Gamperl et al.
CELL BIOLOGY INTERNATIONAL (2016)
Pancreatic Cancer Genetics
Laufey T. Amundadottir
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2016)
Proteinase-activated receptor 2 (PAR2) in hepatic stellate cells - evidence for a role in hepatocellular carcinoma growth in vivo
Franziska Mussbach et al.
MOLECULAR CANCER (2016)
Stromal fibroblasts in preinvasive breast cancer (ductal carcinoma in situ, DCIS) demonstrate a cancer-like procoagulant phenotypic switch that may facilitate invasion
H. Shaker et al.
THROMBOSIS RESEARCH (2016)
PO-51 - Expression of proteins of the tissue factor thrombin pathway is upregulated in the stroma and epithelium of colorectal cancer
H.W. Clouston et al.
THROMBOSIS RESEARCH (2016)
PAR2 Modulators Derived from GB88
Mei-Kwan Yau et al.
ACS MEDICINAL CHEMISTRY LETTERS (2016)
Proteinase-activated receptor 2 promotes TGF-β-dependent cell motility in pancreatic cancer cells by sustaining expression of the TGF-β type I receptor ALK5
Franziska Zeeh et al.
ONCOTARGET (2016)
Deleting the TGF-β receptor in proximal tubules impairs HGF signaling
Stellor Nlandu Khodo et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2016)
Cellular and molecular mechanisms of HGF/Met in the cardiovascular system
Simona Gallo et al.
CLINICAL SCIENCE (2015)
Biased signalling and proteinase-activated receptors (PARs): targeting inflammatory disease
M. D. Hollenberg et al.
BRITISH JOURNAL OF PHARMACOLOGY (2014)
Protease-activated-receptor-2 affects protease-activated-receptor-1-driven breast cancer
Mohammad Jaber et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2014)
Protease-activated receptor 2 suppresses lymphangiogenesis and subsequent lymph node metastasis in a murine pancreatic cancer model
Kun Shi et al.
JOURNAL OF PATHOLOGY (2014)
Proteinase-Activated Receptors Differentially Modulate In Vitro Invasion of Human Pancreatic Adenocarcinoma PANC-1 Cells in Correlation With Changes in the Expression of CDC42 Protein
Liora Segal et al.
PANCREAS (2014)
Novel therapeutic targets for pancreatic cancer
Shing-Chun Tang et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2014)
Perspectives of TGF-beta inhibition in pancreatic and hepatocellular carcinomas
Cindy Neuzillet et al.
ONCOTARGET (2014)
Activation of blood coagulation in cancer: implications for tumour progression
Luize G. Lima et al.
BIOSCIENCE REPORTS (2013)
Proteinase-activated receptors (PARs) - focus on receptor-receptor-interactions and their physiological and pathophysiological impact
Frank Gieseler et al.
CELL COMMUNICATION AND SIGNALING (2013)
Proteinase-activated Receptor-2 Transactivation of Epidermal Growth Factor Receptor and Transforming Growth Factor-β Receptor Signaling Pathways Contributes to Renal Fibrosis
Hyunjae Chung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Transforming Growth Factor-β1 (TGF-β1)-stimulated Fibroblast to Myofibroblast Differentiation Is Mediated by Hyaluronan (HA)-facilitated Epidermal Growth Factor Receptor (EGFR) and CD44 Co-localization in Lipid Rafts
Adam C. Midgley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
被撤回的出版物: Activation of TGF-β1 Promoter by Hepatitis C Virus-Induced AP-1 and Sp1: Role of TGF-β1 in Hepatic Stellate Cell Activation and Invasion (Retracted article. See vol. 14, 2019)
Lance D. Presser et al.
PLOS ONE (2013)
The roles of TGFβ in the tumour microenvironment
Michael Pickup et al.
NATURE REVIEWS CANCER (2013)
Protease-activated receptor 2 promotes experimental liver fibrosis in mice and activates human hepatic stellate cells
Virginia Knight et al.
HEPATOLOGY (2012)
Smad4-mediated TGF-β signaling in tumorigenesis
Guan Yang et al.
International Journal of Biological Sciences (2012)
Novel Role for Proteinase-activated Receptor 2 (PAR2) in Membrane Trafficking of Proteinase-activated Receptor 4 (PAR4)
Margaret R. Cunningham et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
EGFR Signaling Promotes TGFβ-Dependent Renal Fibrosis
Jianchun Chen et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2012)
Targeting proteinase-activated receptors: therapeutic potential and challenges
Rithwik Ramachandran et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
β-Arrestin-2 mediates the proinflammatory effects of proteinase-activated receptor-2 in the airway
Heddie L. Nichols et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Tumor-promoting functions of transforming growth factor-β in progression of cancer
Kohei Miyazono et al.
UPSALA JOURNAL OF MEDICAL SCIENCES (2012)
Interaction of tumor cells with the microenvironment
Hendrik Ungefroren et al.
CELL COMMUNICATION AND SIGNALING (2011)
TGF-β1 induces proteinase-activated receptor 2 (PAR2) expression in endometriotic stromal cells and stimulates PAR2 activation-induced secretion of IL-6
Ako Saito et al.
HUMAN REPRODUCTION (2011)
Proteinase-Activated Receptor 2 Mediates Thermal Hyperalgesia and Is Upregulated in a Rat Model of Chronic Pancreatitis
Wei Zhang et al.
PANCREAS (2011)
Met receptor tyrosine kinase transactivation is involved in proteinase-activated receptor-2-mediated hepatocellular carcinoma cell invasion
Roland Kaufmann et al.
CARCINOGENESIS (2009)
Protease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice
Henri H. Versteeg et al.
CANCER RESEARCH (2008)
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
Sian Jones et al.
SCIENCE (2008)
A small interfering RNA targeting proteinase-activated receptor-2 is effective in suppression of tumor growth in a Panc1 xenograft model
Kentaro Iwaki et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
TGF-β activates Erk MAP kinase signalling through direct phosphorylation of ShcA
Matt K. Lee et al.
EMBO JOURNAL (2007)
Dissecting the role of TGF-beta type I receptor/ALK5 in pancreatic ductal adenocarcinoma:: Smad activation is crucial for both the tumor suppressive and prometastatic function
B. Schniewind et al.
ONCOGENE (2007)
Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-β signaling in cooperation with active Kras expression
Hideaki Ijichi et al.
GENES & DEVELOPMENT (2006)
VEGF, a prosurvival factor, acts in concert with TGF-β1 to induce endothelial cell apoptosis
Giovanni Ferrari et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Autocrine PDGFR signaling promotes mammary cancer metastasis
Martin Jechlinger et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Therapeutic strategies against TGF-β signaling pathway in hepatic fibrosis
XJ Liu et al.
LIVER INTERNATIONAL (2006)
Expression of protease activated receptor-2 (PAR-2) in gastric cancer
D Fujimoto et al.
JOURNAL OF SURGICAL ONCOLOGY (2006)
Dysregulation of growth factor signaling in human hepatocellular carcinoma
K. Breuhahn et al.
ONCOGENE (2006)
Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis
L Xu et al.
GUT (2005)
Hepatocyte growth factor in kidney fibrosis: therapeutic potential and mechanisms of action
YH Liu
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2004)
Regulation of biglycan gene expression by transforming growth factor-β requires MKK6-p38 mitogen-activated protein kinase signaling downstream of smad signaling
H Ungefroren et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Involvement of HB-EGF and EGF receptor transactivation in TGF-β-mediated fibronectin expression in mesangial cells
Y Uchiyama-Tanaka et al.
KIDNEY INTERNATIONAL (2002)
Synergistic cooperation between hypoxia and transforming growth factor-β pathways on human vascular endothelial growth factor gene expression
T Sánchez-Elsner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)