期刊
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
卷 18, 期 6, 页码 -出版社
MDPI
DOI: 10.3390/ijms18061242
关键词
lectin; legume; insecticidal; antimicrobial; cancer
Lectins are a diverse class of proteins distributed extensively in nature. Among these proteins; legume lectins display a variety of interesting features including antimicrobial; insecticidal and antitumor activities. Because lectins recognize and bind to specific glycoconjugates present on the surface of cells and intracellular structures; they can serve as potential target molecules for developing practical applications in the fields of food; agriculture; health and pharmaceutical research. This review presents the current knowledge of the main structural characteristics of legume lectins and the relationship of structure to the exhibited specificities; provides an overview of their particular antimicrobial; insecticidal and antitumor biological activities and describes possible applications based on the pattern of recognized glyco-targets.
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